Prototype
Prototype is a JavaScript framework that aims to ease development of dynamic web applications.
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Rico
Rico provides a very simple interface for registering Ajax request handlers as well as HTML elements or JavaScript objects as Ajax response objects. Multiple elements and/or objects may be updated as the result of one Ajax request.
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MochiKit
MochiKit is a highly documented and well tested, suite of JavaScript libraries that will help you get things done, fast.
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Dojo Toolkit
Dojo is an Open Source toolkit that allows you to easily build dynamic capabilities into web pages and any other environment that supports JavaScript. Dojo provides components that let you make your sites more useable, responsive, and functional.
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Behaviour
Separate Structure (xhtml) from Behavior (javascript)
Solvent
The Solvent is a cross-browser AJAX application toolkit written in JavaScript. The Solvent is provided as modules or as an entire toolkit. The projects focus is to promote robust web applications and enable rapid web development.
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Moo.FX
moo.fx is a superlightweight, ultratiny, megasmall javascript effects library, written with prototype.js.
WZ_DradDrop
A Cross-browser JavaScript DHTML Library which adds Drag Drop functionality to layers and to any desired image
WZ_jsGraphics
High Performance JavaScript Vector Graphics Library.
overLIB
overLIB is a JavaScript library created to enhance websites with small popup information boxes (like tooltips) to help visitors around your website.
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Scriptaculous
Javascript visual effects, togather with prototype.js
SACK
Simple AJAX Code-Kit
Sarissa
Sarissa is an ECMAScript library acting as a cross-browser wrapper for native XML APIs. It offers various XML related goodies like Document instantiation, XML loading from URLs or strings, XSLT transformations, XPath queries etc and comes especially handy for people doing what is lately known as “AJAX” development.
Nifty Corners
A small library for making rounded corners with Javascript.
dp.SyntaxHighlighter
dp.SyntaxHighlighter is a free JavaScript library for source code syntax highlighting.
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AJAX.NET
Michael Schwarz, a .NET developer in Germany has released the latest version of his Ajax .NET Wrapper. This class library simplifies the use of XMLHttp by providing .NET objects that generate the necessary Javascript code.